The same portrait with a visualization of brain activity
btt Corp.

Advancing the
future of health
through brain thermodynamics

btt Corp. is a physics-based, software-driven platform company that turns brain thermodynamics into technology, research and care.

btt Medical Institute

Physician-guided care for patients and families facing complex neurological conditions and oncology-related needs.

  • Noninvasive
  • Personalized protocol
  • Drug-free
  • Proprietary technology
Learn More about btt Medical Institute

btt Wellness Institute

Brain cooling sessions for people focused on sleep, stress reduction, recovery, performance, and vitality.

  • Noninvasive
  • IV Therapy
  • Personalized care
  • Proprietary technology
Learn More about btt Wellness Institute
Brain thermodynamics

Temperature is more than a symptom. It is a biological signal.

Temperature influences how cells repair, how the body responds to illness, how inflammation behaves, and how the brain supports sleep, recovery, and long-term stability.

2003

Yale Discovery

Discovery

The identification of the Brain-Eyelid Thermal Regulatory Tunnel created a new path for noninvasive research into brain thermodynamic signals.

510(k)

FDA Cleared

Technology

In 2010 the Abreu BTT 700 System was cleared by the FDA for continuous temperature monitoring in clinical settings.

116+

Global Patents

btt approach

Our Medical, Wellness and Research platforms apply the same scientific foundation to distinct conditions and needs.

60+

Countries

Global Reach

btt supports patients, partners and institutions from more than 60 countries.

A technology platform for
brain-guided thermodynamics

btt combines noninvasive monitoring of brain thermodynamic signals with investigational thermal protocols, real-time physiological monitoring and physician oversight. Adaptive software helps personalize protocols based on each person's response.

btt technology platform
btt physics-based distinction

Physics-Based
Distinction

Conventional thermal approaches apply temperature to the body. btt starts with the brain. Its platform uses brain-guided feedback to monitor and modulate thermodynamic response in real time.

Advancing the science

Advancing the science of brain-guided thermodynamics

Our goal is to develop solutions that do not yet exist for some of the most debilitating diseases and conditions in the world.

btt Corp. builds its evidence base through peer-reviewed publications, documented cases, and clinical data. We report findings responsibly, and we are clear about what the data can and cannot yet show.

Dr. Marc Abreu at the btt Medical Institute

From one discovery toa broader brain healthecosystem

Dr. Marc Abreu’s discovery of the Brain-Eyelid Thermal Regulatory Tunnel created the foundation for noninvasive brain-guided thermodynamics. Today, btt Corp. builds on that discovery through technology, research, physician-guided care and global partnerships.

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Advancing the conversation
around brain thermodynamics

Explore the latest news, media appearances, interviews and insights on brain thermodynamics, recovery, resilience and the future of brain-guided innovation.

Common questions
about btt Corp.

Quick answers about the ecosystem, the science and how to engage with us.

What is btt Corp.?+

btt Corp. is the parent company behind the btt group. It holds the science, leadership and global structure behind two institutes — btt Medical Institute and btt Wellness Institute — and the research both are built on.

What is brain thermodynamics?+

Brain thermodynamics is a scientific discipline that studies how thermal and energetic dynamics of the brain reflect — and influence — human physiology. It is the technological and scientific foundation of the btt group.

How does btt Corp. connect the btt ecosystem?+

btt Corp. is the institutional layer. btt Medical Institute translates the science into clinical innovation. btt Wellness Institute applies it to human performance and wellbeing. Both draw on the same published research.